Collaborated with a group of the world’s premier scientists, professors, and professionals in the fields of neuroscience and neuroethics.

Synthesized new neuroscience knowledge into a research proposal for a cutting-edge neuroscience experiment.

Engaged in interactive activities with discussions about cognitive neuroscience and neuroethics in a cross-cultural setting through a biophysical lens.

Chloe Furman

Mehlville High School

Class of 2024

Chloe Furman is a rising sophomore at Mehlville High School. She is a hard-working student enrolled in honor classes, with an engaging interest in medicine and neuroscience.

Some extracurricular activities Chloe takes part in would be Marching Band and Environmental Sustainability Club. She is also a part of the Social Justice Club at her school. Chloe enjoys cooking and playing the flute and guitar. She also enjoys participating in volleyball and tennis.

Chloe is very excited to be a part of the Advanced Medical Neuroscience Internship. She has a unique interest for all things neuroscience-related, and has hopes to be a neurologist or a neuroscientist in the future. She believes this program can help her on the path to success, and hopes that the information she learns during this program can help her in her future endeavors in the medical field.

My Neuroscience Training

Leadership Initiatives is a 501(c)(3) nonprofit organization that is dedicated to creating future leaders across the globe through experiential learning. In the Advanced Medical Neuroscience Internship, I worked directly with some of the world’s leading scientists to learn about neuroethics, neurocognitive health, and revolutionary developments in the field.

At the conclusion of the internship, I presented my research proposal to a panel of judges including Dr. James Giordano, Dr. John Shook, and Dr. Michael Heinrich. Respectively, these judges are the Chair of Georgetown University’s Neuroethics Studies Program, Philosopher and Bowie State University Professor, and Coburg University’s School of Design Dean of Studies.

In order to address the lack of research surrounding bulimia nervosa, I presented this proposal to this distinguished panel of judges. I proposed research helping to correlate the consumption of carbohydrates to the exacerbation of the effects of bulimia nervosa. My research aimed to expose the link between the consumption of sugars and an addiction-like euphoria that could further the effects of the eating disorder.

My Research Proposal

My research posed the answer to the question “Do simple carbohydrates activate neural network pathways in the brains of people with bulimia nervosa analogously to people with alcohol addiction?”

In order to answer this question, I devised a methodology that centered itself around different neurotransmitters such as tryptophan, serotonin, and dopamine. After studying these transmitters, I proposed a comparative study that focused around two subgroups each similar in as many demographics as possible. These groups would undergo testing by fMRIU and SPECT to scan for their neural circuits. This would allow for a post-sugar-consumption comparison where the same brain tests could scan for any changes in neural activity.

Our anticipated findings suggest that sugars and simple carbohydrates will create a spike in neurotransmitters, a reaction similar to alcohol addiction. This opens up the pathway for more research correlating carbohydrate intake and a loss or change of mood.

The Frontier of Neuroscience

Deep Brain Stimulation

I had the unique opportunity to speak with Dr. Michael Okun, founder of the University of Florida’s movement disorders program.

Within his work, Dr. Okun utilizes Deep Brain Stimulation (DBS), which operates like a pacemaker within the brain and is often inserted via conscious surgery

Electrodes are put in the brain to regulate electrical signals and help with conditions like Epilepsy, Parkinson’s Disease, Dystonia, Obsessive Compulsive Disorder, and Essential Tremor.

Quantitative Neuroscience Research Methods

Dr. Sebastian Sauer discussed how data is mined from social media and how natural language processing is able to interpret the tone of a post and discern the original intent of the poster.

We explored how this method of quantifying word choice can contextualize how people feel in a broader societal exchange, allowing for the extension of research to the biophysical sphere.

Then we connected this metrics to its implications of what is occuring in the brain when interacting with social media over time, revealing its role along the spectrum of involvement.

Internship Highlights

Dr. James Giordano

I had the chance to work and collaborate directly with Dr. James Giordano, Chief of Georgetown University’s Neuroethics Studies Program. In addition to his involvement with a variety of educational institutions, Dr. Giordano is the author of over 350 publications in neuroscience and neuroethics.

During our first meeting, I got a crash course on the biological mind of our species. I learned about the major role our subconscious plays in our thinking, and how these thoughts rarely breach our consciousness.

This new knowledge prompted a debate over free will, whether we maintain true control over our mental functions, and the crucial implications for both our individuals and social lives.

Neuroanatomy

I learned about the anatomy and physiology of the brain in a demonstrative lecture from Dr. Giordano.

The brain is protected by the skull and is composed of the cerebrum, cerebellum, and brain stem. It embodies an individual’s mind and soul, in conjunction with governing intelligence, creativity, emotion, and memory.

This amazing organ is not only of use to us in life but in death as well. After explaining the brain’s anatomy and physiology, Dr. Giordano outlined the use of Brain Banks, which are organizations that accept brains for research that is instrumental in mitigating the effects and prevalence of neurocognitive disease.

Brain~Mind Interventions

Brain~Mind Interventions are utilized for the treatment, wellness, and enhancement of the mind and brain. These interventions can be categorized into “Low-tech” and “High-tech” Brain~Mind Interventions.

“Low-tech” Brain~Mind Interventions allow you to modify the interactions between the brain and mind through accessible and non-invasive techniques. In contrast, “High-tech” Brain~Mind Interventions are less accessible and can involve invasive procedures.

This new knowledge allowed me to assess the intersection between brain, mind, and body and how they can work together to improve the wellbeing of an individual.

Experts & Mentors

Along with Dr. Giordano, I had the opportunity to work closely with Dr. Rachel Wurzman, a Fellow with the Center for Neuroscience & Society and Postdoctoral Research Fellow in Neurology with the Laboratory of Neural Stimulation at the University of Pennsylvania.

Dr. Wurzman lent her expertise of neuroplasticity, neurodiversity, and neuroethics to help our team develop our research proposal.

In addition to Dr. Wurzman’s assistance, my team worked directly with Professor Heather Aranyi, leading communication coach and faculty in Northwestern University’s Farley Center for Entrepreneurship. Professor Aranyi helped us develop the story behind our proposal, properly contextualize our research, and hone our presentation skills.